Regeneron is conducting a study enrolling male participants with haemophilia B

Honey-B aims to evaluate disease characteristics in people with haemophilia B who are receiving FIX prophylaxis.


This website provides information about a study, Honey-B, for boys and men with haemophilia B. Haemophilia B is a rare genetic disease characterised by abnormally low amounts of functional Factor IX (factor nine) protein. Factor IX (FIX) is a protein made naturally in the body and helps the blood to form clots to stop bleeding. FIX is expressed by a gene located on the X chromosome. Men have only one X chromosome, while women have two X chromosomes. Because of this, severe haemophilia more often affects men as they do not have a second copy of the gene. People with moderate and severe haemophilia B have spontaneous bleeding inside the body, pain and heavy bleeding after a cut or injury.