Regeneron is conducting a study enrolling male participants with Hemophilia B.

Honey-B aims to evaluate disease characteristics in people with hemophilia B that are receiving FIX prophylaxis. This website provides information about a study, Honey-B, for boys and men with hemophilia B. Hemophilia B is a rare genetic disease characterized by abnormally low amounts of functional Factor IX (factor nine) protein. Factor IX (FIX) is a protein made naturally in the body and helps the blood form clots to stop bleeding. FIX is expressed by a gene located on the X chromosome. Men have only one X chromosome while women have two X chromosomes. Because of this, severe hemophilia more often affects men as they do not have a second copy of the gene. People with moderate and severe hemophilia B have spontaneous bleeding inside the body, pain, and heavy bleeding after a cut or injury.